Longitudinal monitoring of disease burden and response using ctDNA from dried blood spots in xenograft models

2 Datasets 1 Publication

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001008650	This dataset contains 8 .bam files of shallow WGS (~0.1×) from fresh frozen tumour tissues of four matched patients and first generation PDX models. Sequencing reads were aligned to the 1000 Genomes Project GRCh37-derived reference genome using the BWA aligner (v.0.07.17; CRUK-CI alignment pipeline).	Illumina HiSeq 4000	8
EGAD00001008651	This dataset contains paired-end fastq sequencing files (n=212) from shallow WGS of 106 dried blood spot (DBS) samples, containing 91 DBS collected from OV04 ovarian cancer PDX mice, 10 DBS collected from healthy non-tumour bearing NSG mice, and 5 DBS generated from whole blood samples from 4 OV04 ovarian cancer patients.	Illumina NovaSeq 6000	106

Publications	Citations
Longitudinal monitoring of disease burden and response using ctDNA from dried blood spots in xenograft models. Sauer CM, Heider K, Belic J, Boyle SE, Hall JA, Couturier DL, An A, Vijayaraghavan A, Reinius MA, Hosking K, Vias M, Rosenfeld N, Brenton JD. EMBO Mol Med 14: 2022 e15729	6