Extreme intratumor heterogeneity and driver evolution in mismatch repair deficient gastro-esophageal cancer

1 Dataset 1 Publication

Click on a Dataset ID in the table below to learn more, and to find out who to contact about access to these data

Dataset ID	Description	Technology	Samples
EGAD00001004594	The dataset includes multi-region exome sequencing (MSeq) of four resected treatment naïve mismatch repair deficient gastro-esophageal cancers. Paired-end sequencing was performed on the Illumina HiSeq 2500 or NovaSeq 6000 with a target depth of 200X. Seven primary tumor regions along with tumor-adjacent non malignant tissue were subjected to MSeq. An additional two lymph node metastases were also included from each of two cases.	Illumina HiSeq 2500 Illumina NovaSeq 6000	35

Publications	Citations
Extreme intratumour heterogeneity and driver evolution in mismatch repair deficient gastro-oesophageal cancer. von Loga K, Woolston A, Punta M, Barber LJ, Griffiths B, Semiannikova M, Spain G, Challoner B, Fenwick K, Simon R, Marx A, Sauter G, Lise S, Matthews N, Gerlinger M. Nat Commun 11: 2020 139	30